NIR/ICG – Near-Infrared Fluorescence
Fluorescence Imaging
Your Real-Time Guide for Everyday Use
In endoscopic surgery, detecting structures earlier and differentiating them better is a necessity. The imaging technology has to replace the missing view of the open site. Alongside an optimal image, it is helpful to receive additional information that increases the precision of the surgical technique. This information is supplied, for instance, by NIR/ICG fluorescence imaging – an OPAL1® technology from KARL STORZ.
The use of indocyanine green (ICG) together with light at wavelengths in the near infrared range (NIR) permits visualizing anatomic structures, for instance. KARL STORZ considers fluorescence technology a future standard imaging technique.
NIR/ICG Visualization Modes
The Rubina components offer users various new modes for visualizing the NIR/ICG signal. This includes the overlay of NIR/ICG data onto the standard white light image or alternatively the monochromatic visualization of the infrared signal alone.
All-in-One Solutions
Thanks to modular architecture, new 4K, NIR/ICG, and LED components can be added to the existing IMAGE1 S™ camera platform. The IMAGE1 S™ RUBINA components offer users new options and a series of advantages to support them in their daily routine.
There is mORe to discover
Example Applications of NIR/ICG
Visualization of Perfusion
New meta-analysis regarding the use of NIR/ICG in colorectal surgery
Perfusion assessment is important in various medical disciplines. With IMAGE1 S™ RUBINA and ICG administration, ischemic areas, perfusion, and vascular structures can be displayed in real time, thereby enabling the surgeon to respond intraoperatively.
Example applications:
- Rapid perfusion assessment of a planned resection zone as well as of the subsequent anastomosis, e.g., in colon1 or esophageal resection and gastric bypass2
- Display of the cystic artery in cholangiography2
- Visualization of liver segments3 and lung segments4
- Visualization of vessels within and outside of tumor tissue for the improved definition of tumor margins in otorhinolaryngology5
- Multidisciplinary use in laparoscopic, endoscopic, and open surgery
1Koh et al., Fluorescent Angiography Used to Evaluate the Perfusion Status of Anastomosis in Laparoscopic Anterior Resection, 2016
2Boni et al., Clinical Applications of Indocyanine Green (ICG) Enhanced Fluorescence in Laparoscopic Surgery, 2015
3Diana M et al Superselective Intra-arterial Hepatic Injection of Indocyanine Green (ICG) for Fluorescence Image-guided Segmental Positive Staining: Experimental Proof of the Concept, 2017
4Pischik et al., NIR / ICG Fluorescence Imaging in Thoracoscopic Segmentectomy, 2018
5Schmidt et al., Near-Infrared Endoscopy with Indocyanine Green in Otolaryngology, 2016
Bile Visualization
Due to its hepatobiliary excretion, ICG collects in the gallbladder and bile ducts. This allows, for instance, the rapid and easy identification of the biliary anatomy in cholecystectomy.
Example applications:
- Reduced surgical duration with ICG when compared to standard cholangiographies.1 Facilitated differentiation between cystic duct and common bile duct.2
- Visual perceptual illusion is the cause of 97% of bile duct injuries; moreover, 19% of all patients exhibit abnormal anatomic variations of the gallbladder.3
- Display of intraoperative bile leakage with ICG, e.g., following partial hepatectomy.
1Dip et al., Cost analysis and effectiveness comparing the routine use of intraoperative fluorescent cholangiography with fluoroscopic cholangiogram in patients undergoing laparoscopic cholecystectomy, 2014
2Boni et al., NIR/ICG Fluorescence Imaging in Laparoscopic Surgery, Doctor-to-Doctor Manual ENDO-PRESS®, (ISBN 978-3-89756-933-1)
3Dip F., et al., EndoPress Silverbrochure, Fluorescence Cholangiography, 2017